Biopharma Enterprise · Synthetic Control Arms (SCA) · PopSIM™ · Sovereign Defense & Dual-Use
Biopharma, Synthetic Control Arms & Defense
Accelerate Phase II/III clinical development with zero-placebo synthetic control arms compliant with FDA 2023 RWE guidance. Deploy sovereign air-gapped cognitive compute clusters, autonomous in silico hypothesis generation, and NATO STANAG-ready dual-use CBRN pathogen surveillance.
In Silico Cohort Modeling & Real-World Evidence
Synthetic Control Arms & Clinical Acceleration
Eliminate ethical recruitment roadblocks in oncology and rare disease trials while cutting development timelines and capital expenditure.
Pharma Enterprise & Synthetic Control Arms (SCA)
In Silico Cohort Modeling, Protocol Optimization & Virtual Control Groups
- Zero-Placebo Synthetic Control Arms (SCA): High-dimensional propensity score matched external cohorts conforming to FDA 2023 RWE guidance.
- PopSIM™ In Silico Clinical Acceleration: Multi-omic population trajectory simulation to identify responder sub-phenotypes prior to Phase II/III commit.
- PharmaLink™ Precision Matcher: Deterministic candidate identification across multi-modal biomarker strata.
- AutoResearcher-HYPO™ Engine: Autonomous Bayesian exploration of off-target efficacy and secondary indication discovery.
- Zero-Egress Sovereign Architecture: Full compliance with GDPR Art. 9/89 and HIPAA Expert Determination (Zero raw data egress).
Pharma Trial Match & Patient Stratification PRO
Precision Candidate Identification & Decentralized Cohort Enrichment
- Multimodal Stratification Matrix: Real-time alignment of complex genetic, proteomic, and clinical phenotypes against study protocol parameters.
- Site-Agnostic Matching: Seamless decentralized patient identification without multi-site recruitment bottlenecks.
- Predictive Screen Failure Prevention: Deterministic filtering of hidden exclusionary comorbidities to reduce late-stage dropouts.
- Complete HIPAA Expert De-Identification: Patient data is preserved under cryptographic tokenization; zero raw PHI transferred.
Pharma Starter & Translational Growth
Aggregate Feasibility & Early Target Safety Profiling
- Target Tractability & Safety Deconvolution: Rapid in silico assessment of on-target and off-target liabilities across human physiological networks.
- Cohort Feasibility Counts: High-speed statistical population queries under data-use agreements; counts only, never individual records.
- Chemotherapy & ADME Kinetic Modeling: Pharmacokinetic drug interaction and multi-system toxicity tensors.
- IND Filing Acceleration: Structured, auditable computational evidence dossiers supporting regulatory submissions.
Zero-Egress Critical Infrastructure · Air-Gapped Compute
Sovereign Bare Cognitive Engine & Defense
Air-gapped deterministic reasoning cores engineered for defense agencies, critical infrastructure, tactical field hospitals, and national biothreat surveillance.
Sovereign Bare Cognitive Engine Core
Deterministic Reasoning Core for Sovereign, Tactical & Critical Infrastructure
Further functions
- Dual-Use CBRN / GERN Pathogen & Biothreat SurveillanceAvailable to Qualified Entities
- Classified-network air-gap deploymentAvailable by application
- Bare Cognitive Engine: Pure deterministic inference runtime for air-gapped environments without external cloud dependencies.
- Tactical Field Medicine AI: Fully autonomous diagnostic reasoning engineered for denied, degraded, and zero-bandwidth environments.
- GERN Global Epidemic Radar: Early-warning anomaly detection for novel biological threats and atypical clinical syndromic clusters.
- Hardened Cryptographic Security: Architected to meet NATO STANAG, FIPS 140-3 Level 3, and sovereign data boundary mandates.
- Full Baseline & Advanced Capabilities: Undisclosed by design, disclosed on application under government NDA.
Tactical Field Node Appliance
Austere Environment & Mobile Medical Sovereign Unit
- Air-Gapped Autonomous Operation: Local inferencing runtime with zero dependence on commercial cloud or constant network uplinks.
- Low-Bandwidth Satellite Sync: Burst cryptographic telemetry for epidemiological outbreak correlation.
- CBRN Anomaly Detection: Integrated sensor tensor mapping atypical physiological presentations to potential biological or chemical agents.
- Hardware Enclave Root of Trust: Physical tamper-resistant enclosure with cryptographic memory wiping on unauthorized physical compromise.
Programmatic Deterministic Verification
Developer REST API & Platform Engine
Integrate the DeepSensi deterministic reasoning core directly into your clinical applications, laboratory workflows, or biopharma pipelines via our authenticated REST API.
Developer API & Integration Platform
Programmatic SIL-4 Deterministic Inference & Verification API
- AHV (Anti-Hallucination Verification): Deterministic verification of medical text generated by LLMs against verified biomedical literature.
- BCA (Audit Ledger): Immutable cryptographic transaction ledger (RSA-2048 / SHA-256) tracking every reasoning step.
- RSCH (Deep Biomedical Research): High-speed evidence retrieval across 47+ indexed scientific and clinical databases.
- ARSCH (AutoResearcher-HYPO™): Bayesian hypothesis generation and target-disease association exploration API.
- REST API & Webhooks: Authenticated endpoints (
X-DS-API-Key) with predictable sub-second latency and granular rate limiting.
Biopharma, Clinical Research & Defense Ledger
Enterprise Ancillary & Add-on Modules
Synthetic Control Arms & PopSIM™
Sponsors and CROs
External control cohorts and in silico cohort simulation under data-use agreements; high-dimensional propensity matching and cohort-scale digital twin generation compliant with FDA 2023 RWE guidance.
Pharma Trial Match
Sponsors and research networks
Trial matching for sponsors across Phase II/III pipelines, with precision biomarker match identification and direct patient intake coordination.
Pharma Starter & Growth
Biotech startups and venture discovery
Aggregate answers to protocol feasibility questions; a sponsor receives statistical population counts only, never an individual patient record.
PharmaLink Enterprise Partner
Sponsors with pharmacovigilance teams
Continuous safety-signal review from public FDA adverse-event databases (FAERS) and autonomous hypothesis generation for new indications.
Tactical Field Node
Defense, disaster-response and civil protection
An offline field node designed to operate over low-bandwidth satellite links, with GERN outbreak surveillance for public health teams.
Legal & Medico-Legal Audit Desk
Risk managers, medical-legal experts and insurers
Read-only cryptographic access to the tamper-evident record of what was checked, when, by whom, and on which biomedical sources.
Developer API Suite
Health software and bioinformatics developers
Source verification of clinical text generated by external models, tamper-evident audit logging, and automated literature synthesis.
